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M94A0354.TXT
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Document 0354
DOCN M94A0354
TI Neutralization of HIV-1 [see comments]
DT 9412
AU Golding H; D'Souza MP; Bradac J; Mathieson B; Fast P; Laboratory of
Retrovirus Research, FDA/CBER, Bethesda, Maryland; 20892.
SO AIDS Res Hum Retroviruses. 1994 Jun;10(6):633-43. Unique Identifier :
AIDSLINE MED/94355107
CM Comment in: AIDS Res Hum Retroviruses 1994 Jun;10(6):631-2
AB A Workshop on Neutralization of HIV-1: Technology and reagents for
analysis of prophylactic vaccines clinical trials, sponsored by the Food
and Drug Administration (FDA) and the Division of AIDS, National
Institute of Allergy and Infectious Diseases (NIAID), National
Institutes of Health (NIH), was held on April 19-20, 1993, in Bethesda,
Maryland. This workshop brought together researchers who are involved in
the development, testing, and evaluation of HIV-1 prophylactic vaccines.
The major objectives were (1) to discuss critically the different
neutralization and binding assays that are currently used in the
evaluation of immune sera; (2) to identify assays that will measure the
most relevant antibodies, which are likely to predict neutralization of
primary isolates; and (3) to identify well-characterized reference
reagents, which could be used to standardize neutralization assays used
in laboratories around the world.
DE Acquired Immunodeficiency Syndrome/IMMUNOLOGY/*PREVENTION & CONTROL
AIDS Serodiagnosis/*STANDARDS AIDS Vaccines/*STANDARDS Enzyme-Linked
Immunosorbent Assay Human *HIV-1/IMMUNOLOGY/ISOLATION & PURIF
Leukocytes, Mononuclear/MICROBIOLOGY Neutralization Tests Reference
Standards T-Lymphocytes/MICROBIOLOGY MEETING REPORT JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).